B2M Knockout THP-1 Cell Line
78389 BPS Bioscience 2 vials 6500 EUR
Description: B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing from THP-1 cells.

CIITA Knockout THP-1 Cell Line
78390 BPS Bioscience 2 vials 6500 EUR
Description: CIITA (Class II Transactivator) has been genetically removed from THP-1 cells using CRISPR/Cas9 genome editing.

TCR/B2M Knockout Jurkat Cell Line
78552 BPS Bioscience 2 vials 8645 EUR
Description: This cell line is a double knockout of TCR (T Cell Receptor) and B2M (Beta-2-Microglobulin). First, the TRAC (T-Cell Receptor Alpha Constant) and the TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRα/β chains were genetically removed by CRISPR/Cas9 genome editing from Jurkat cells to generate the TCR Knockout Jurkat cell Line (BPS Bioscience #78539). These TCR knockout cells were then used to generate a new cell line in which B2M was also genetically removed by CRISPR/Cas9 genome editing.

FCGR2A (CD32A) Knockout Jurkat Cell Line
78549 BPS Bioscience 2 vials 6500 EUR
Description: The FCGR2A Knockout Jurkat cell line was generated by CRISPR/Cas9 genome editing to remove FCGR2A (CD32A), the gene encoding protein FcγRIIa (Fragment crystallizable gamma receptor II a, also known as FcGRIIa, Fc-gamma-RIIa, and CD32A).

B2M/CIITA Double Knockout THP-1 Cell Line
78391 BPS Bioscience 2 vials 9500 EUR
Description: Both B2M (Beta-2-Microglobulin) and CIITA (Class II Transactivator) have been genetically removed from THP-1 cells using CRISPR/Cas9 genome editing.

B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line
78363 BPS Bioscience 2 vials 11095 EUR
Description: B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing from NFAT Luciferase Reporter Jurkat cells. Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity.

TCR Knockout NFAT-Luciferase Reporter Jurkat Cell Line
78556 BPS Bioscience 2 vials 12205 EUR
Description: This cell line is a knockout of TCR (T Cell Receptor). The TRAC (T-Cell Receptor Alpha Constant) and TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRα/β chains were genetically removed by CRISPR/Cas9 genome editing from recombinant Jurkat cells stably expressing the firefly luciferase gene under the control of NFAT response elements.This cell line has been functionally validated and does not respond to anti-CD3 agonist antibodies, as opposed to parental NFAT-Luciferase Reporter Jurkat cells (BPS Bioscience #60621).

TCR/B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line
78557 BPS Bioscience 2 vials 16695 EUR
Description: This cell line is a double knockout of TCR (T Cell Receptor) and B2M (Beta-2-Microglobulin). First, the TRAC (T-Cell Receptor Alpha Constant) and the TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRα/β chains were genetically removed by CRISPR/Cas9 genome editing from NFAT Luciferase Reporter Jurkat cells to generate the TCR Knockout NFAT Luciferase Reporter Jurkat cell Line (BPS Bioscience #78556). These TCR knockout cells were used to generate a new cell line in which B2M was also genetically removed by CRISPR/Cas9 genome editing. _x000D_Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity. 

CRISPR/Cas9 Kinase Knockout Lentivirus Library (Array Format)
78487 BPS Bioscience 200 µl x 649 7700 EUR
Description: The CRISPR/Cas9 Kinase Knockout Lentivirus Library (Array Format) targets 619 human kinases and pseudo-kinases.bpsbioscience.com/media/wysiwyg/Kinases/Kinase_Library_-_List_Kinases_Pseudokinases_06-15-2022.xlsx Download the table to view all available kinases. The Array consists of a series of vials, with each vial containing a mixture of integrating CRISPR/Cas9 lentiviral particles targeting 5 sgRNAs for a specific gene (1 vial per gene, 5 sgRNAs per gene). The Array also includes a total of 150 control sgRNAs that do not target any gene (combined into 30 vials containing 5 control sgRNAs per vial). Thus, the Array contains a total of 649 vials and 3,245 sgRNAs.The lentiviruses are replication incompetent, VSV-G pseudotyped lentiviral particles ready to infect almost all types of mammalian cells, including primary and non-dividing cells. The SIN (self-inactivation) lentiviral backbone contains the Cas9 gene (Streptococcus pyogenes CRISPR associated protein 9) driven by an EF1a promoter, an sgRNA driven by a U6 promoter, and a puromycin selection marker.The lentiviruses integrate randomly into the cellular genome to express both Cas9 and the sgRNAs. Because the lentiviruses contain Cas9, they can be used in any target cell regardless of whether the cells already express Cas9. Puromycin selection ensures high expression of both Cas9 and the sgRNAs. Knockout efficiencies will depend on the cell type and the gene of interest. Stable CRISPR/Cas9 knockout cell lines can also be generated following limiting dilution.The library is delivered with a User Manual booklet.

Gene Knock-Out HR Targeting Vector [MCS1-EF1α-RFP-T2A-Puro-pA-MCS2]
HR110PA-1 SBI 10 ug 933 EUR

Gene Knock-Out HR Targeting Vector [MCS1-EF1a-GFP-T2A-Puro-pA-MCS2]
HR410PA-1 SBI 10 ug 933 EUR

Gene Knock-Out HR Targeting Vector [MCS1-EF1a-RFP-T2A-Hygro-pA-MCS2]
HR510PA-1 SBI 10 ug 933 EUR

Gene Knock-Out HR Targeting Vector with TK selection [MCS1-LoxP-EF1α-GFP-T2A-Puro-P2A-hsvTK-pA-LoxP-MCS2]
HR210PA-1 SBI 10 ug 1071 EUR

Gene Knock-Out HR Targeting Vector w/Dual Selection Markers (GFP+Puro) and Negative Selection (TK) Against Random Integration
HR700PA-1 SBI 10 µg 1071 EUR

Gene Knock-Out HR Targeting Vector w/Dual Selection Markers (RFP+Hygro) and Negative Selection (TK) Against Random Integration
HR710PA-1 SBI 10 µg 1071 EUR

Gene Knock-Out HR Targeting Vector w/Single Selection Marker (Blasticidin) and Negative Selection (TK) Against Random Integration
HR720PA-1 SBI 10 µg 1071 EUR

Mouse Genetic suppressor element 1, Gse1 ELISA KIT
ELI-48300m Lifescience Market 96 Tests 1038 EUR

Human Genetic suppressor element 1, GSE1 ELISA KIT
ELI-27963h Lifescience Market 96 Tests 988.8 EUR

Geneticin (G418)
20-abx082452 Abbexa
  • 226.80 EUR
  • 360.00 EUR
  • 100 mg
  • 1 g

Geneticin (G418)
20-abx082533 Abbexa
  • 226.80 EUR
  • 292.80 EUR
  • 100 mg
  • 1 g

Geneticin (G418, (>98% pure))
ABT-800-01 Alpha Diagnostics 1 g 196.8 EUR

Geneticin (G418, (>98% pure))
ABT-800-05 Alpha Diagnostics 5 g 489.6 EUR

Geneticin, G-418 Sulfate
A2513-1000 ApexBio 1 g 157.2 EUR
Description: G-418 is an elongation inhibitor of 80 S ribosomes [1].G418 is an aminoglycoside antibiotic, it has a wide spectrum of activity and is active against bacteria, yeasts, fungi, algae, plant and even animal cells.

Geneticin, G-418 Sulfate
A2513-5000 ApexBio 5 g 351.6 EUR
Description: G-418 is an elongation inhibitor of 80 S ribosomes [1].G418 is an aminoglycoside antibiotic, it has a wide spectrum of activity and is active against bacteria, yeasts, fungi, algae, plant and even animal cells.

Mouse tPA Genetically Deficient Lung
IMSTPAGDLG Innovative research each 256 EUR
Description: Mouse tPA Genetically Deficient Lung

*Mouse PAI-1 Genetically Deficient Lung
IMSPAI1GDLG2 Innovative research each 190 EUR
Description: *Mouse PAI-1 Genetically Deficient Lung

Mouse tPA Genetically Deficient Brain
IMSTPAGDBR Innovative research each 256 EUR
Description: Mouse tPA Genetically Deficient Brain

Mouse tPA Genetically Deficient Heart
IMSTPAGDHT Innovative research each 256 EUR
Description: Mouse tPA Genetically Deficient Heart

Mouse tPA Genetically Deficient Liver
IMSTPAGDLR Innovative research each 256 EUR
Description: Mouse tPA Genetically Deficient Liver

QuantiSir General Gene Knockdown Quantification Kit
P-5001 EpiGentek
  • 945.66 EUR
  • 376.20 EUR
  • 625.90 EUR
  • 96 Assays
  • 48 Assays
  • 96 Assays

*Mouse PAI-1 Genetically Deficient Brain
IMSPAI1GDBR2 Innovative research each 190 EUR
Description: *Mouse PAI-1 Genetically Deficient Brain

*Mouse PAI-1 Genetically Deficient Heart
IMSPAI1GDHT2 Innovative research each 190 EUR
Description: *Mouse PAI-1 Genetically Deficient Heart

*Mouse PAI-1 Genetically Deficient Liver
IMSPAI1GDLR2 Innovative research each 190 EUR
Description: *Mouse PAI-1 Genetically Deficient Liver

Mouse tPA Genetically Deficient Kidney
IMSTPAGDKD Innovative research each 256 EUR
Description: Mouse tPA Genetically Deficient Kidney

*Mouse tPA Genetically Deficient Plasma
IMSTPAGDP100UL Innovative research each 348 EUR
Description: *Mouse tPA Genetically Deficient Plasma

Mouse tPA Genetically Deficient Spleen
IMSTPAGDSP Innovative research each 256 EUR
Description: Mouse tPA Genetically Deficient Spleen

Mouse Factor IX Genetically Deficient Lung
IMSFIXGDLG Innovative research each 256 EUR
Description: Mouse Factor IX Genetically Deficient Lung

Mouse Factor XI Genetically Deficient Lung
IMSFXIGDLG Innovative research each 256 EUR
Description: Mouse Factor XI Genetically Deficient Lung

*Mouse PAI-1 Genetically Deficient Kidney
IMSPAI1GDKD2 Innovative research each 100 EUR
Description: *Mouse PAI-1 Genetically Deficient Kidney

*Mouse PAI-1 Genetically Deficient Plasma
IMSPAI1GDPNAC50UL Innovative research each 228 EUR
Description: *Mouse PAI-1 Genetically Deficient Plasma

*Mouse PAI-1 Genetically Deficient Spleen
IMSPAI1GDSP2 Innovative research each 190 EUR
Description: *Mouse PAI-1 Genetically Deficient Spleen

Mouse Factor IX Genetically Deficient Brain
IMSFIXGDBR Innovative research each 256 EUR
Description: Mouse Factor IX Genetically Deficient Brain

Mouse Factor IX Genetically Deficient Heart
IMSFIXGDHT Innovative research each 256 EUR
Description: Mouse Factor IX Genetically Deficient Heart

Mouse Factor IX Genetically Deficient Liver
IMSFIXGDLR Innovative research each 256 EUR
Description: Mouse Factor IX Genetically Deficient Liver

Mouse Factor XI Genetically Deficient Brain
IMSFXIGDBR Innovative research each 256 EUR
Description: Mouse Factor XI Genetically Deficient Brain

Mouse Factor XI Genetically Deficient Heart
IMSFXIGDHT Innovative research each 256 EUR
Description: Mouse Factor XI Genetically Deficient Heart

Mouse Factor XI Genetically Deficient Liver
IMSFXIGDLR Innovative research each 256 EUR
Description: Mouse Factor XI Genetically Deficient Liver

Mouse Factor XII Genetically Deficient Lung
IMSFXIIGDLG Innovative research each 256 EUR
Description: Mouse Factor XII Genetically Deficient Lung

Mouse Factor IX Genetically Deficient Kidney
IMSFIXGDKD Innovative research each 256 EUR
Description: Mouse Factor IX Genetically Deficient Kidney

*Mouse Factor IX Genetically Deficient Plasma
IMSFIXGDP100UL Innovative research each 348 EUR
Description: *Mouse Factor IX Genetically Deficient Plasma

*Mouse Factor IX Genetically Deficient Plasma
IMSFIXGDP50UL Innovative research each 228 EUR
Description: *Mouse Factor IX Genetically Deficient Plasma

Mouse Factor IX Genetically Deficient Spleen
IMSFIXGDSP Innovative research each 256 EUR
Description: Mouse Factor IX Genetically Deficient Spleen

Mouse Factor XI Genetically Deficient Kidney
IMSFXIGDKD Innovative research each 256 EUR
Description: Mouse Factor XI Genetically Deficient Kidney

Mouse Factor XI Genetically Deficient Plasma
IMSFXIGDP50UL Innovative research each 228 EUR
Description: Mouse Factor XI Genetically Deficient Plasma

Mouse Factor XI Genetically Deficient Spleen
IMSFXIGDSP Innovative research each 256 EUR
Description: Mouse Factor XI Genetically Deficient Spleen

Mouse Factor XII Genetically Deficient Brain
IMSFXIIGDBR Innovative research each 256 EUR
Description: Mouse Factor XII Genetically Deficient Brain

Mouse Factor XII Genetically Deficient Heart
IMSFXIIGDHT Innovative research each 256 EUR
Description: Mouse Factor XII Genetically Deficient Heart

Mouse Factor XII Genetically Deficient Liver
IMSFXIIGDLR Innovative research each 256 EUR
Description: Mouse Factor XII Genetically Deficient Liver

TARGATT? Knock-in iPSC Generation (Master Cell Line)
AST-1100 Applied StemCell 1 vial of 1X10^6 cells Ask for price
Description: 6 month

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)
AST-1200 Applied StemCell 1 Kit Ask for price
Description: 12 month

Mouse C1 Inhibitor Genetically Deficient Lung
IMSC1INHGDLG Innovative research each 256 EUR
Description: Mouse C1 Inhibitor Genetically Deficient Lung

Mouse Factor XII Genetically Deficient Kidney
IMSFXIIGDKD Innovative research each 256 EUR
Description: Mouse Factor XII Genetically Deficient Kidney

*Mouse Factor XII Genetically Deficient Plasma
IMSFXIIGDP50UL Innovative research each 228 EUR
Description: *Mouse Factor XII Genetically Deficient Plasma

Mouse Factor XII Genetically Deficient Spleen
IMSFXIIGDSP Innovative research each 256 EUR
Description: Mouse Factor XII Genetically Deficient Spleen

Mouse Kininogen Genetically Deficient Lung
IMSKNGGDLG Innovative research each 256 EUR
Description: Mouse Kininogen Genetically Deficient Lung

Mouse C1 Inhibitor Genetically Deficient Brain
IMSC1INHGDBR Innovative research each 256 EUR
Description: Mouse C1 Inhibitor Genetically Deficient Brain

Mouse C1 Inhibitor Genetically Deficient Heart
IMSC1INHGDHT Innovative research each 256 EUR
Description: Mouse C1 Inhibitor Genetically Deficient Heart

*Mouse C1 Inhibitor Genetically Deficient Liver
IMSC1INHGDLR Innovative research each 256 EUR
Description: *Mouse C1 Inhibitor Genetically Deficient Liver

Mouse Kininogen Genetically Deficient Brain
IMSKNGGDBR Innovative research each 256 EUR
Description: Mouse Kininogen Genetically Deficient Brain

Mouse Kininogen Genetically Deficient Heart
IMSKNGGDHT Innovative research each 256 EUR
Description: Mouse Kininogen Genetically Deficient Heart