BMP signaling agonist sb4

T7799-10mg TargetMol Chemicals 10mg Ask for price
Description: BMP signaling agonist sb4

BMP signaling agonist sb4

T7799-1g TargetMol Chemicals 1g Ask for price
Description: BMP signaling agonist sb4

BMP signaling agonist sb4

T7799-1mg TargetMol Chemicals 1mg Ask for price
Description: BMP signaling agonist sb4

BMP signaling agonist sb4

T7799-50mg TargetMol Chemicals 50mg Ask for price
Description: BMP signaling agonist sb4

BMP signaling agonist sb4

T7799-5mg TargetMol Chemicals 5mg Ask for price
Description: BMP signaling agonist sb4

Human Notch Signaling Pathway

HNOT-I Real Time Primers 1 set 657.6 EUR

Human Statin Signaling Library

HSTAT-I Real Time Primers 1 set 657.6 EUR

Hh Signaling Pathway Antagonist

1659-1 Biovision each 216 EUR

Rat Bdnf Signaling Primer Library

RBDNF-I Real Time Primers 1 set 774 EUR

Rat Gdnf Signaling Primer Library

RGDNF-I Real Time Primers 1 set 774 EUR

Mouse Ras Signaling Primer Library

MRAS-I Real Time Primers 1 set 657.6 EUR

Mouse p53 Signaling Primer Library

MTPS-I Real Time Primers 1 set 540 EUR

Mouse WNT Signaling Primer Library

MWNT-I Real Time Primers 1 set 657.6 EUR

Mouse BMP Signaling Primer Library

MBMP-I Real Time Primers 1 set 657.6 EUR

ER Signaling Protein Detection Set

PSI-1814 ProSci 1 Set 752.1 EUR
Description: The endoplasmic reticulum (ER) is an organelle composed of an interconnected network of tubules, vesicles and cisternae found in all eukaryotic cells. It is involved in several specialized processes such as protein translation, folding, and transport of proteins to be used in the cell membrane or secreted from the cell. Accumulation of malfolded proteins in the ER activates the unfolded protein response (UPR) and the upregulation of the ER molecular chaperones GRP78 and GRP 94. These proteins are normally bound to ER transmembrane proteins such as IRE1p and ATF6 but ER stress causes their dissociation. This allows IRE1p, a serine-threonine protein kinase, to transduce the unfolded protein signal from the ER to the nucleus. IRE1p also has an endoribonuclease activity that is required to splice X-box binding protein (XBP1) mRNA, converting it to a potent UPR transcriptional activator. ER stress also causes the cleavage of ATF6, yielding a cytosolic fragment which migrates to the nucleus and together with XBP-1, activates transcription of UPR-responsive genes. Depletion of IRE1p through the expression of a dominant negative form of IRE1p has no effect on transfected cells, but cell death via apoptosis occurs under stress conditions that cause unfolded proteins to accumulate in the ER.;;For images please see PDF data sheet

Human BMP Signaling Primer Library

HBMP-I Real Time Primers 1 set 657.6 EUR

Human MAP Kinase Signaling Library

HMAP-I Real Time Primers 1 set 657.6 EUR

Human Ras Signaling Primer Library

HRAS-I Real Time Primers 1 set 657.6 EUR

Human TNF Signaling Primer Library

HTNF-I Real Time Primers 1 set 657.6 EUR

Human p53 Signaling Primer Library

HTPS-I Real Time Primers 1 set 540 EUR

Human WNT Signaling Primer Library

HWNT-I Real Time Primers 1 set 657.6 EUR

Mouse Gdnf Signaling Primer Library

MGDNF-I Real Time Primers 1 set 657.6 EUR

Mouse Bdnf Signaling Primer Library

MBDNF-I Real Time Primers 1 set 657.6 EUR

Mouse CREB Signaling Primer Library

MCREB-I Real Time Primers 1 set 657.6 EUR

Mouse EGFR Signaling Primer Library

MEGFR-I Real Time Primers 1 set 657.6 EUR

TOR Signaling Pathway Detection Set

PSI-1805 ProSci 1 Set 1287.6 EUR
Description: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle progression through its ability to integrate signals from nutrient levels and growth factors. TOR regulation is accomplished through a network of various activators and repressors. It is phosphorylated by Akt, whose activity is indirectly inhibited by the lipid phosphatase PTEN. TOR is normally associated with the regulatory proteins RAPTOR, a scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation, and GΒL, which stimulates TOR’s kinase activity towards downstream proteins. It is further regulated by the proteins Rheb, TSC1 and TSC2, which act to modulate TOR activity. The downstream targets of TOR are thought to be the ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins (4EBPs) whose activation leads to increased protein translation and cell growth.;;For images please see PDF data sheet

Human EGFR Signaling Primer Library

HEGFR-I Real Time Primers 1 set 657.6 EUR

Human ERBB Signaling Primer Library

HERBB-I Real Time Primers 1 set 657.6 EUR

Human GDNF Signaling Primer Library

HGDNF-I Real Time Primers 1 set 657.6 EUR

Human IL17 Signaling Primer Library

HIL17-I Real Time Primers 1 set 657.6 EUR

Human BDNF Signaling Primer Library

HBDNF-I Real Time Primers 1 set 657.6 EUR

Human cAMP Signaling Primer Library

HCAMP-I Real Time Primers 1 set 657.6 EUR

Human CREB Signaling Primer Library

HCREB-I Real Time Primers 1 set 657.6 EUR

Human PDGF Signaling Primer Library

HPDGF-I Real Time Primers 1 set 657.6 EUR

Human SMAD Signaling Primer Library

HSMAD-I Real Time Primers 1 set 657.6 EUR

Human VEGF Signaling Primer Library

HVEGF-I Real Time Primers 1 set 657.6 EUR

Cyclopamine (Hedgehog signaling blocker)

SIH-226-1MG Stressmarq 1 mg 162 EUR
Description: The substance Cyclopamine is a hedgehog signaling blocker. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 5 mM in ethanol.

Cyclopamine (Hedgehog signaling blocker)

SIH-226-5MG Stressmarq 5 mg 414 EUR
Description: The substance Cyclopamine is a hedgehog signaling blocker. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 5 mM in ethanol.

Mouse Hippo Signaling Primer Library

MHPO-I Real Time Primers 1 set 657.6 EUR

Mouse Notch Signaling Primer Library

MNOT-I Real Time Primers 1 set 657.6 EUR

Human Hippo Signaling Primer Pathway

HHPO-I Real Time Primers 1 set 657.6 EUR

Rat Integrin Signaling Primer Library

RINT-I Real Time Primers 1 set 1008 EUR

Agouti Signaling Protein (ASIP) Antibody

abx122198-100ug Abbexa 100 ug 469.2 EUR

Agouti Signaling Protein (ASIP) Antibody

20-abx148376 Abbexa
  • 510.00 EUR
  • 410.40 EUR
  • 100 ug
  • 50 ug

Agouti Signaling Protein (ASIP) Antibody

20-abx005235 Abbexa
  • 493.20 EUR
  • 710.40 EUR
  • 218.40 EUR
  • 376.80 EUR
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Mouse Hypoxia Signaling Primer Library

MHYP-I Real Time Primers 1 set 657.6 EUR

DiscoveryProbe? NF-?B Signaling Library

L1044-.1 ApexBio 100 uL/well(10 mM solution) 1730.4 EUR

DiscoveryProbe? NF-?B Signaling Library

L1044-.25 ApexBio 250 uL/well(10 mM solution) 3052.8 EUR

DiscoveryProbe? NF-?B Signaling Library

L1044-5 ApexBio 5 mg/well 3970.8 EUR

Human Hypoxia Signaling Primer Library

HHYP-I Real Time Primers 1 set 657.6 EUR

DiscoveryProbe? Neuronal Signaling Library

L1026-.1 ApexBio 100 uL/well(10 mM solution) 5961.6 EUR

DiscoveryProbe? Neuronal Signaling Library

L1026-.25 ApexBio 250 uL/well(10 mM solution) 10639.2 EUR

DiscoveryProbe? Neuronal Signaling Library

L1026-5 ApexBio 5 mg/well 13840.8 EUR

Mouse Integrin Signaling Primer Library

MINT-I Real Time Primers 1 set 891.6 EUR

Human Estrogen Signaling Primer Library

HESR-I Real Time Primers 1 set 774 EUR

Human Hedgehog Signaling Primer Library

HHOG-I Real Time Primers 1 set 774 EUR

Human Integrin Signaling Primer Library

HINT-I Real Time Primers 1 set 657.6 EUR

Human Androgen Signaling Primer Library

HAND-I Real Time Primers 1 set 657.6 EUR

Myc Reporter Kit (Myc Signaling Pathway)

60519 BPS Bioscience 500 rxns. 625 EUR
Description: The Myc Pathway Reporter kit is designed for monitoring the activity of the Myc signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for c- Myc and Myc luciferase reporter vector. Inside the cells, c-Myc will bind to Max, translocate to the nucleus, and induce expression of the Myc luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized Myc responsive elements located upstream of a minimal promoter. The Myc reporter is premixed with constitutively-expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency._x000D_The kit also includes a non-inducible firefly luciferase vector premixed with constitutivelyexpressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical for determining pathway-specific effects and background luciferase activity.

Mouse TGF Beta Signaling Primer Library

MTGFB-I Real Time Primers 1 set 657.6 EUR