il 1
IL-1 beta, rat recombinant |
|||
P1019-1 | ApexBio | 1 mg | 8745.6 EUR |
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar biological properties. |
|||
Anti-IL1R2/Il 1 Rii Antibody |
|||
A03106-1 | BosterBio | 1 ml | 476.4 EUR |
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human. |
|||
Recombinant Rat IL-1 Beta Protein |
|||
PROTQ63264-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues. |
|||
Canine IL-1 beta Recombinant Protein |
|||
R00101-1 | BosterBio | 5ug/vial | 310.8 EUR |
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Canine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast. |
|||
Canine IL-1 alpha Recombinant Protein |
|||
R01144-1 | BosterBio | 5ug/vial | 310.8 EUR |
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Canine IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast. |
|||
IL-17A |
|||
91014-1 | BPS Bioscience | 5 µg | 95 EUR |
Description: Human secreted interleukin_x000D_17 A (IL-17A) also known as, IL-17 and_x000D_cytotoxic T lymphocyte antigen 8 (CTLA8)_x000D_GenBank Accession No. NM_ 002190, a.a_x000D_20-155(end), expressed in an e. coli_x000D_expression system. This protein exists_x000D_naturally as a homodimer; M.W. = 17.5 kDa_x000D_(monomer); 35 kDa dimer |
|||
IL-1-beta Interleukin-1 betaHuman Recombinant Protein |
|||
PROTP01584-1 | BosterBio | Regular: 10ug | 380.4 EUR |
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques. |
|||
Recombinant Murine IL-17 (IL-17A) Protein |
|||
PROTQ62386-1 | BosterBio | 25ug | 380.4 EUR |
Description: The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant murine IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains. |
|||
Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
|||
EMI2200-1 | AssayPro | 96 Well Plate | 572.4 EUR |
Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
|||
EI2200-1 | AssayPro | 96 Well Plate | 572.4 EUR |
Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit |
|||
EI2301-1 | AssayPro | 96 Well Plate | 572.4 EUR |
IL-2 |
|||
E13-013-1 | EnoGene | 10μg | 193.2 EUR |
IL-4 |
|||
E13-015-1 | EnoGene | 10μg | 193.2 EUR |
IL-6 |
|||
E13-016-1 | EnoGene | 10μg | 193.2 EUR |
IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag |
|||
PROTP10749-1 | BosterBio | Regular: 25ug | 380.4 EUR |
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques. |
|||
IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag |
|||
PROTP16598-1 | BosterBio | Regular: 20ug | 380.4 EUR |
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa. |
|||
IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag |
|||
PROTP01582-1 | BosterBio | Regular: 20ug | 380.4 EUR |
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
|||
IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag |
|||
PROTP01583-1 | BosterBio | Regular: 20ug | 380.4 EUR |
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques. |
|||
Anti-IL-31 Antibody |
|||
A08339-1 | BosterBio | 100ug/vial | 400.8 EUR |
Anti-IL-17B Antibody |
|||
A10846-1 | BosterBio | 100ul | 476.4 EUR |
Description: Rabbit Polyclonal Antibody for IL-17B Antibody (IL17B) detection.tested for IHC in Human, Rat. |
|||
Anti-IL-6 Antibody |
|||
A00102-1 | BosterBio | 100ug | 518.4 EUR |
Description: Rabbit Polyclonal IL-6 Antibody. Validated in Neu, IHC, WB and tested in Human. |
|||
IL-1beta, human recombinant |
|||
P1018-1 | ApexBio | 1 mg | 6073.2 EUR |
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells |
|||
IL-2, human recombinant |
|||
P1020-1 | ApexBio | 1 mg | 1387.2 EUR |
Description: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes and is produced by activated CD4+ and CD8+ T cells, gamma ? T cells, B cells, dendritic cells and eosinophils. IL-2 plays a critical role in immune responses against pathogenic infection |
|||
IL-3, human recombinant |
|||
P1021-1 | ApexBio | 1 mg | 4820.4 EUR |
Description: Interleukin 3 (IL-3) is a pleiotropic cytokine produced by activated T cells, mast cells and eosinophils, and stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, and committed progenitor cells of the megakaryocyte |
|||
IL-4, murine recombinant |
|||
P1022-1 | ApexBio | 1 mg | 5404.8 EUR |
Description: IL-4 is a pleiotropic cytokine produced by activated T lymphocytes, basophils, mast cells and bone marrow stromal cells. IL-4 plays an important role in the regulation of isotype switching, differentiation of precursor T helper cells and induction of IgE production in B lymphocytes. |
|||
IL-6, rat recombinant |
|||
P1023-1 | ApexBio | 1 mg | 8328 EUR |
Description: Interleukin-6 (IL-6) is a pleiotropic cytokine produced by activated T cells, monocytes, fibroblasts, endothelial cells, keratinocytes and macrophages, and plays an critical role in host defense by regulating immune and inflammatory responses. |
|||
IL-7, human recombinant |
|||
P1024-1 | ApexBio | 1 mg | 8328 EUR |
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells. |
|||
IL-7, murine recombinant |
|||
P1025-1 | ApexBio | 1 mg | 8328 EUR |
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells. |
|||
IL-1RA Interleukin-1 Receptor Antagonist Mouse Recombinant Protein |
|||
PROTP25085-1 | BosterBio | Regular: 20ug | 380.4 EUR |
Description: IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa. ;The IL1ra is purified by proprietary chromatographic techniques. |
|||
His-IL-3 |
|||
E13-014-1 | EnoGene | 10μg | 193.2 EUR |
His-IL-10 |
|||
E13-019-1 | EnoGene | 10μg | 193.2 EUR |
His-IL-22 |
|||
E13-028-1 | EnoGene | 10μg | 255.6 EUR |
IL-2-Fc |
|||
E13-m007-1 | EnoGene | 10μg | 372 EUR |
Anti-IL-3R beta Antibody |
|||
A02219-1 | BosterBio | 100ul | 476.4 EUR |
Description: Rabbit Polyclonal Antibody for IL-3R beta Antibody (CSF2RB) detection.tested for WB in Human, Mouse, Rat. |
|||
Anti-IL-2/IL2 Antibody |
|||
A00387-1 | BosterBio | 100ug/vial | 352.8 EUR |
Anti-IL-8 Monoclonal Antibody |
|||
A00423-1 | BosterBio | 100ul | 476.4 EUR |
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat. |
|||
Anti-IL-22/IL22 Antibody |
|||
A00963-1 | BosterBio | 100ug/vial | 352.8 EUR |
IL-10, human recombinant protein |
|||
P1028-1 | ApexBio | 1 mg | 8077.2 EUR |
Description: Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the synthesis of proinflammatory cytokines such as IL-1 and TNF-? and proliferation of T cells |
|||
IL-15, human recombinant protein |
|||
P1029-1 | ApexBio | 1 mg | 6406.8 EUR |
Description: Interleukin 15 (IL-15) is an immunomodulating cytokine mainly produced by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells and stimulates the proliferation of T lymphocytes. |
|||
IL-17A, human recombinant protein |
|||
P1030-1 | ApexBio | 1 mg | 4987.2 EUR |
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO). |
|||
IL-17A, rat recombinant protein |
|||
P1031-1 | ApexBio | 1 mg | 4987.2 EUR |
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO) |
|||
IL-18, human recombinant protein |
|||
P1032-.1 | ApexBio | 100 µg | 936 EUR |
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures. |
|||
IL-18, human recombinant protein |
|||
P1032-1 | ApexBio | 1 mg | 6073.2 EUR |
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures. |
|||
IL-21, human recombinant protein |
|||
P1033-1 | ApexBio | 1 mg | 7826.4 EUR |
Description: Interleukin-21 (IL-21) is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. IL-21 induces the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells, apoptotic effects in naïve B-cells. |
|||
Anti-IL-6 Monoclonal Antibody |
|||
M00102-1 | BosterBio | 100ug | 546 EUR |
Description: Mouse Monoclonal IL-6 Antibody. Validated in Flow Cytometry, WB and tested in Human. |
|||
Anti-IL-17A Monoclonal Antibody |
|||
M00421-1 | BosterBio | 100ug | 546 EUR |
Description: Mouse Monoclonal IL-17A Antibody. Validated in WB and tested in Human. |
|||
Recombinant Rat IL-5 Protein |
|||
PROTQ08125-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. |
|||
Recombinant Human IL-24 Protein |
|||
PROTQ13007-1 | BosterBio | 20ug | 380.4 EUR |
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag. |
|||
Recombinant Murine IL-31 Protein |
|||
PROTQ6EAL8-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues. |
|||
Recombinant Human IL-31 Protein |
|||
PROTQ6EBC2-1 | BosterBio | 10ug | 380.4 EUR |
Description: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues. |
|||
Recombinant Murine IL-17F Protein |
|||
PROTQ7TNI7-1 | BosterBio | 25ug | 380.4 EUR |
Description: IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains. |
|||
Recombinant Human IL-17D Protein |
|||
PROTQ8TAD2-1 | BosterBio | 25ug | 380.4 EUR |
Description: IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains. |
|||
Recombinant Murine IL-21 Protein |
|||
PROTQ9ES17-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the γ chain (γc) found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues. |
|||
Recombinant Human IL-22 Protein |
|||
PROTQ9GZX6-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains. |
|||
Recombinant Human IL-17E Protein |
|||
PROTQ9H293-1 | BosterBio | 25ug | 380.4 EUR |
Description: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains. |
|||
Recombinant Human IL-20 Protein |
|||
PROTQ9NYY1-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains. |
|||
Recombinant Human IL-19 Protein |
|||
PROTQ9UHD0-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer. |
|||
Recombinant Murine IL-4 Protein |
|||
PROTP07750-1 | BosterBio | 20ug | 380.4 EUR |
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues. |
|||
Recombinant Murine IL-7 Protein |
|||
PROTP10168-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues. |
|||
Recombinant Murine IL-9 Protein |
|||
PROTP15247-1 | BosterBio | 10ug | 380.4 EUR |
Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant murine IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins. |