Mapping the signal sequence-binding site on SRP reveals a significant role for the NG domain.
We current proof that the sign recognition particle (SRP) acknowledges sign sequences through the NG area on the SRP54 protein subunit. Utilizing a just lately developed cross-linking methodology (Fancy, D. A., and Kodadek, T. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6020-6024; Correction (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1317), we discover that sign peptides cross-link to the Escherichia coli SRP protein Ffh (the homologue of the mammalian SRP54 subunit) through the NG area.
Inside the NG area, the cross-linking web site maps to the ras-like C-terminal subdomain termed the G area. This consequence stands in distinction to earlier research, which concluded based mostly on nascent chain cross-linking that the sign sequence certain to the adjoining M area. As unbiased proof of a direct binding interplay between the NG area and the sign sequence, we discover that the NG area of Ffh binds sign peptides as an remoted entity. Our outcomes recommend that the NG area types a considerable a part of the binding web site for the sign sequence.
p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Built-in Pulsed Secure Isotope Labeling With Amino Acids in Cell Tradition (pSILAC) and Subsequent Era Sequencing (NGS) Analyses.
We decided the impact of p53 activation on de novo protein synthesis utilizing quantitative proteomics (pulsed secure isotope labeling with amino acids in cell tradition/pSILAC) within the colorectal most cancers cell line SW480. This was mixed with mRNA and noncoding RNA expression analyses by subsequent technology sequencing (RNA-, miR-Seq). Moreover, genome-wide DNA binding of p53 was analyzed by chromatin-immunoprecipitation (ChIP-Seq).
Thereby, we recognized differentially regulated proteins (542 up, 569 down), mRNAs (1258 up, 415 down), miRNAs (111 up, 95 down) and lncRNAs (270 up, 123 down). Modifications in protein and mRNA expression ranges confirmed a constructive correlation (r = 0.50, p < 0.0001). In whole, we detected 133 direct p53 goal genes that had been differentially expressed and displayed p53 occupancy within the neighborhood of their promoter.
Extra transcriptionally induced genes displayed occupied p53 binding websites (4.3% mRNAs, 7.2% miRNAs, 6.3% lncRNAs, 5.9% proteins) than repressed genes (2.4% mRNAs, 3.2% miRNAs, 0.8% lncRNAs, 1.9% proteins), suggesting oblique mechanisms of repression. Round 50% of the down-regulated proteins displayed seed-matching sequences of p53-induced miRNAs within the corresponding 3′-UTRs.
Furthermore, proteins repressed by p53 considerably overlapped with these beforehand proven to be repressed by miR-34a. We confirmed up-regulation of the novel direct p53 goal genes LINC01021, MDFI, ST14 and miR-486 and confirmed that ectopic LINC01021 expression inhibits proliferation in SW480 cells. Moreover, KLF12, HMGB1 and CIT mRNAs had been confirmed as direct targets of the p53-induced miR-34a, miR-205 and miR-486-5p, respectively.
According to the lack of p53 operate throughout tumor development, elevated expression of KLF12, HMGB1 and CIT was detected in superior phases of most cancers. In conclusion, the combination of a number of omics strategies allowed the excellent identification of direct and oblique effectors of p53 that present new insights and leads into the mechanisms of p53-mediated tumor suppression.
Subsequent-generation sequencing (NGS) for evaluation of microbial water high quality: present progress, challenges, and future alternatives.
Water high quality is an emergent property of a posh system comprised of interacting microbial populations and launched microbial and chemical contaminants. Research leveraging next-generation sequencing (NGS) applied sciences are offering new insights into the ecology of microbially mediated processes that affect contemporary water high quality reminiscent of algal blooms, contaminant biodegradation, and pathogen dissemination. As well as, sequencing strategies focusing on small subunit (SSU) rRNA hypervariable areas have allowed identification of signature microbial species that function bioindicators for sewage contamination in these environments.
Past amplicon sequencing, metagenomic and metatranscriptomic analyses of microbial communities in contemporary water environments reveal the genetic capabilities and interaction of waterborne microorganisms, shedding gentle on the mechanisms for manufacturing and biodegradation of poisons and different contaminants. This evaluate discusses the challenges and advantages of making use of NGS-based strategies to water high quality analysis and evaluation.
We’ll contemplate the suitability and biases inherent within the software of NGS as a screening software for evaluation of organic dangers and talk about the potential and limitations for direct quantitative interpretation of NGS knowledge.
Secondly, we’ll study case research from latest literature the place NGS based mostly strategies have been utilized to matters in water high quality evaluation, together with growth of bioindicators for sewage air pollution and microbial supply monitoring, characterizing the distribution of toxin and antibiotic resistance genes in water samples, and investigating mechanisms of biodegradation of dangerous pollution that threaten water high quality. Lastly, we offer a brief evaluate of rising NGS platforms and their potential purposes to the subsequent technology of water high quality evaluation instruments.
Inference of Markovian properties of molecular sequences from NGS knowledge and purposes to comparative genomics.
Subsequent-generation sequencing (NGS) applied sciences generate massive quantities of quick learn knowledge for a lot of totally different organisms. The truth that NGS reads are typically quick makes it difficult to assemble the reads and reconstruct the unique genome sequence. For clustering genomes utilizing such NGS knowledge, word-count based mostly alignment-free sequence comparability is a promising method, however for this method, the underlying anticipated phrase counts are important
Mouse Androgen Receptor (AR) ELISA Kit |
|||
| RDR-AR-Mu-48Tests | Reddot Biotech | 48 Tests | 640.8 EUR |
Mouse Androgen Receptor (AR) ELISA Kit |
|||
| RDR-AR-Mu-96Tests | Reddot Biotech | 96 Tests | 890.4 EUR |
Rat Androgen Receptor (AR) ELISA Kit |
|||
| RDR-AR-Ra-48Tests | Reddot Biotech | 48 Tests | 669.6 EUR |
Rat Androgen Receptor (AR) ELISA Kit |
|||
| RDR-AR-Ra-96Tests | Reddot Biotech | 96 Tests | 931.2 EUR |
Human Androgen Receptor (AR) ELISA Kit |
|||
| RD-AR-Hu-48Tests | Reddot Biotech | 48 Tests | 600 EUR |
Human Androgen Receptor (AR) ELISA Kit |
|||
| RD-AR-Hu-96Tests | Reddot Biotech | 96 Tests | 830.4 EUR |
Mouse Androgen Receptor (AR) ELISA Kit |
|||
| RD-AR-Mu-48Tests | Reddot Biotech | 48 Tests | 613.2 EUR |
Mouse Androgen Receptor (AR) ELISA Kit |
|||
| RD-AR-Mu-96Tests | Reddot Biotech | 96 Tests | 850.8 EUR |
Rat Androgen Receptor (AR) ELISA Kit |
|||
| RD-AR-Ra-48Tests | Reddot Biotech | 48 Tests | 640.8 EUR |
Rat Androgen Receptor (AR) ELISA Kit |
|||
| RD-AR-Ra-96Tests | Reddot Biotech | 96 Tests | 890.4 EUR |
Ar/ Rat Ar ELISA Kit |
|||
| ELI-04146r | Lifescience Market | 96 Tests | 1063.2 EUR |
AR Antibody |
|||
| CSB-PA001975KA01HU- | Cusabio | 402 EUR | |
|
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, ICC;WB:1:500-1:1000, IHC:1:50-1:100, ICC:1:50-1:100 |
|||
AR Antibody |
|||
| CSB-PA001975KA01HU-100ul | Cusabio | 100ul | 466.8 EUR |
|
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, ICC;WB:1:500-1:1000, IHC:1:50-1:100, ICC:1:50-1:100 |
|||
AR Antibody |
|||
| 1-CSB-PA056943 | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100 |
|||
AR Antibody |
|||
| 1-CSB-PA05979A0Rb | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
|||
AR Antibody |
|||
| DF6783 | Affbiotech | 200ul | 420 EUR |
AR Antibody |
|||
| AF6137 | Affbiotech | 200ul | 420 EUR |
AR Antibody |
|||
| AF6927 | Affbiotech | 100ul | 420 EUR |
AR siRNA |
|||
| 20-abx908237 | Abbexa |
|
|
AR siRNA |
|||
| 20-abx908238 | Abbexa |
|
|
AR Antibody |
|||
| 1-CSB-PA006094 | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000 |
|||
AR Antibody |
|||
| 1-CSB-PA011255 | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000 |
|||
AR Antibody |
|||
| 1-CSB-PA011256 | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/40000 |
|||
AR Antibody |
|||
| 1-CSB-PA011257 | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000 |
|||
AR Antibody |
|||
| 1-CSB-PA011258 | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000 |
|||
AR antibody |
|||
| 70R-35838 | Fitzgerald | 100 ug | 392.4 EUR |
|
Description: Rabbit polyclonal AR antibody |
|||
AR Antibody |
|||
| 32572-100ul | SAB | 100ul | 302.4 EUR |
AR antibody |
|||
| 10R-2031 | Fitzgerald | 100 ul | 483.6 EUR |
|
Description: Mouse monoclonal AR antibody |
|||
AR-A014418 |
|||
| A3184-10 | ApexBio | 10 mg | 153.6 EUR |
|
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor. |
|||
AR-A014418 |
|||
| A3184-5.1 | ApexBio | 10 mM (in 1mL DMSO) | 147.6 EUR |
|
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor. |
|||
AR-A014418 |
|||
| A3184-50 | ApexBio | 50 mg | 321.6 EUR |
|
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor. |
|||
AR-A014418 |
|||
| A3184-S | ApexBio | Evaluation Sample | 97.2 EUR |
|
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor. |
|||
AR-C155858 |
|||
| A3185-10 | ApexBio | 10 mg | 1189.2 EUR |
|
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members. |
|||
AR-C155858 |
|||
| A3185-5 | ApexBio | 5 mg | 733.2 EUR |
|
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members. |
|||
AR-C155858 |
|||
| A3185-50 | ApexBio | 50 mg | 3360 EUR |
|
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members. |
|||
AR A014418 |
|||
| 20-abx076761 | Abbexa |
|
|
AR Antibody |
|||
| ABD6783 | Lifescience Market | 100 ug | 525.6 EUR |
AR siRNA |
|||
| 20-abx900461 | Abbexa |
|
|
AR Antibody |
|||
| BF0349 | Affbiotech | 200ul | 540 EUR |
AR Antibody |
|||
| BF0418 | Affbiotech | 200ul | 540 EUR |
AR-C155858 |
|||
| B2743-1 | Biovision | 1 mg | 417.6 EUR |
AR 231453 |
|||
| B3269-10 | ApexBio | 10 mg | 294 EUR |
|
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors. |
|||
AR 231453 |
|||
| B3269-5 | ApexBio | 5 mg | 214.8 EUR |
|
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors. |
|||
AR 231453 |
|||
| B3269-5.1 | ApexBio | 10 mM (in 1mL DMSO) | 234 EUR |
|
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors. |
|||
AR-08 |
|||
| HY-U00371 | MedChemExpress | 20mg | 16126.8 EUR |
AR-A014418 |
|||
| HY-10512 | MedChemExpress | 50mg | 410.4 EUR |
AR-9281 |
|||
| HY-111151 | MedChemExpress | 5mg | 253.2 EUR |
AR-C155858 |
|||
| HY-13248 | MedChemExpress | 10mM/1mL | 579.6 EUR |
AR 231453 |
|||
| HY-15564 | MedChemExpress | 10mM/1mL | 192 EUR |
pCDNA3.1-AR |
|||
| PVT18102 | Lifescience Market | 2 ug | 360 EUR |
Clematichinenoside AR |
|||
| TBW00371 | ChemNorm | 10mg | 1016.4 EUR |
ar-Tumerone |
|||
| TBW01373 | ChemNorm | 5mg | Ask for price |
AR Antibody |
|||
| F42684-0.4ML | NSJ Bioreagents | 0.4 ml | 379 EUR |
AR Antibody |
|||
| F42850-0.4ML | NSJ Bioreagents | 0.4 ml | 379 EUR |
KAF/AR/ Rat KAF/ AR ELISA Kit |
|||
| ELA-E0006r | Lifescience Market | 96 Tests | 1063.2 EUR |
AR Polyclonal Antibody |
|||
| ABP53269-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR |
|||
AR Polyclonal Antibody |
|||
| ABP53269-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR |
|||
AR Polyclonal Antibody |
|||
| ABP53269-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR |
|||
AR Blocking Peptide |
|||
| DF6783-BP | Affbiotech | 1mg | 234 EUR |
AR-42J cells |
|||
| C0018004 | Addexbio | One Frozen vial | 546 EUR |
AR Conjugated Antibody |
|||
| C32572 | SAB | 100ul | 476.4 EUR |
AR-beta3 Antibody |
|||
| AF9021 | Affbiotech | 200ul | 420 EUR |
AR Polyclonal Antibody |
|||
| ES4268-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES4268-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5938-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5938-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5939-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for IHC, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5939-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for IHC, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5940-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse. This antibody is tested and validated for IHC, IF, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5940-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse. This antibody is tested and validated for IHC, IF, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5941-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| ES5941-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
AR Polyclonal Antibody |
|||
| 41904-100ul | SAB | 100ul | 302.4 EUR |
AR Polyclonal Antibody |
|||
| 41904-50ul | SAB | 50ul | 224.4 EUR |
Beta3-AR Antibody |
|||
| 3939-200 | Biovision | 424.8 EUR | |
Beta3-AR Antibody |
|||
| 3939-30T | Biovision | 175.2 EUR | |
AR-beta3 Antibody |
|||
| 44295-100ul | SAB | 100ul | 302.4 EUR |
AR-beta3 Antibody |
|||
| 44295-50ul | SAB | 50ul | 224.4 EUR |
AR Polyclonal Antibody |
|||
| 40609-100ul | SAB | 100ul | 302.4 EUR |
AR Polyclonal Antibody |
|||
| 40609-50ul | SAB | 50ul | 224.4 EUR |
AR Polyclonal Antibody |
|||
| 40610-100ul | SAB | 100ul | 302.4 EUR |
AR Polyclonal Antibody |
|||
| 40610-50ul | SAB | 50ul | 224.4 EUR |
AR Polyclonal Antibody |
|||
| ABP54939-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S650 |
|||
AR Polyclonal Antibody |
|||
| ABP54939-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S650 |
|||
AR Polyclonal Antibody |
|||
| ABP54939-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S650 |
|||
AR Polyclonal Antibody |
|||
| ABP54940-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S213 |
|||
AR Polyclonal Antibody |
|||
| ABP54940-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S213 |
|||
AR Polyclonal Antibody |
|||
| ABP54940-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S213 |
|||
AR Polyclonal Antibody |
|||
| ABP54941-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse. This AR antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S94 |
|||
AR Polyclonal Antibody |
|||
| ABP54941-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse. This AR antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S94 |
|||
AR Polyclonal Antibody |
|||
| ABP54941-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse. This AR antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S94 |
|||
AR Polyclonal Antibody |
|||
| ABP54942-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of Y363 |
|||
AR Polyclonal Antibody |
|||
| ABP54942-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of Y363 |
|||
AR Polyclonal Antibody |
|||
| ABP54942-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of Y363 |
|||
AR (pS213) Antibody |
|||
| 20-abx000354 | Abbexa |
|
|
AR (pS650) Antibody |
|||
| 20-abx000355 | Abbexa |
|
|
AR- beta3 Antibody |
|||
| ABF9021 | Lifescience Market | 100 ug | 525.6 EUR |
AR Blocking Peptide |
|||
| BF0418-BP | Affbiotech | 1mg | 234 EUR |
AR-M 1896 |
|||
| B5328-1 | ApexBio | 1 mg | 583.2 EUR |
|
Description: Binding IC50: 1.76 nM for rGalR2; 879 nM for hGalR1Galanin is a 29-aa neuropeptide with a complex role in pain processing. Galanin receptor subtypes are present in dorsal root ganglia and spinal cord with a differential distribution. |
|||
AR-C 102222 |
|||
| B5504-10 | ApexBio | 10 mg | 505.2 EUR |
AR-C 102222 |
|||
| B5504-50 | ApexBio | 50 mg | 1940.4 EUR |
Netarsudil (AR-13324) |
|||
| B7807-2 | ApexBio | 2 mg | 366 EUR |
|
Description: Ki: 0.43141.3 nMNetarsudil (AR-13324) is a ROCK inhibitor.The Rho kinases are serine/threonine protein kinases existing as 2 isoforms, ROCK1 and ROCK2, which are widely expressed in various tissues, such as the trabecular meshwork. |
|||
Netarsudil (AR-13324) |
|||
| B7807-5 | ApexBio | 5 mg | 532.8 EUR |
|
Description: Ki: 0.43141.3 nMNetarsudil (AR-13324) is a ROCK inhibitor.The Rho kinases are serine/threonine protein kinases existing as 2 isoforms, ROCK1 and ROCK2, which are widely expressed in various tissues, such as the trabecular meshwork. |
|||
Recombinant Human AR |
|||
| P0503 | FN Test | 100ug | 626.83 EUR |
|
Description: Recombinant Human protein for AR |
|||
anti-AR (1A9D12) |
|||
| LF-MA30225 | Abfrontier | 100 ul | 583.2 EUR |
|
Description: Mouse Monoclonal to AR |
|||
AR-C102222 (hydrochloride) |
|||
| HY-12122A | MedChemExpress | 10mg | 1410 EUR |
AR ELISA Kit |
|||
| STJ150094 | St John's Laboratory | 1 kit | 494.4 EUR |
|
Description: The kit is a competitive enzyme immunoassay for in vitro quantitative measurement of T in serum, plasma and other biological fluids |
|||
Anti-AR antibody |
|||
| STJ118653 | St John's Laboratory | 100 µl | 332.4 EUR |
Anti-AR Antibody |
|||
| STJ193178 | St John's Laboratory | 200 µl | 236.4 EUR |
Anti-AR antibody |
|||
| STJ22662 | St John's Laboratory | 100 µl | 332.4 EUR |
|
Description: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
|||
Anti-AR antibody |
|||
| STJ97233 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: AR is a protein encoded by the AR gene which is approximately 99,1 kDa. AR is localised to the nucleus and cytoplasm. It is involved in deubiquitination, gene expression, metabolism of proteins and the nuclear receptor transcription pathway. It functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR is expressed in the liver, nervous system, blood, muscle and kidney. Mutations in the AR gene may result in prostate cancer. STJ97233 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR protein. |
|||
Anti-AR antibody |
|||
| STJ91659 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: Rabbit polyclonal to AR. |
|||
Anti-AR antibody |
|||
| STJ91660 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: Rabbit polyclonal to AR. |
|||
Anti-AR antibody |
|||
| STJ91661 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: Rabbit polyclonal to AR. |
|||
Anti-AR antibody |
|||
| STJ91662 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: Rabbit polyclonal to AR. |
|||
Anti-AR antibody |
|||
| STJ97845 | St John's Laboratory | 100 µl | 280.8 EUR |
|
Description: Mouse monoclonal to AR. |
|||
Anti-AR antibody |
|||
| STJ97846 | St John's Laboratory | 100 µl | 280.8 EUR |
|
Description: Mouse monoclonal to AR. |
|||
Anti-AR antibody |
|||
| STJ114876 | St John's Laboratory | 100 µl | 332.4 EUR |
|
Description: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
|||
AR (Ab-650) Antibody |
|||
| CSB-PA227367- | Cusabio | 402 EUR | |
|
Description: A polyclonal antibody against AR (Ab-650). Recognizes AR (Ab-650) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
|||
AR (Ab-650) Antibody |
|||
| CSB-PA227367-100ul | Cusabio | 100ul | 379.2 EUR |
|
Description: A polyclonal antibody against AR (Ab-650). Recognizes AR (Ab-650) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
|||
AR (Ab-363) Antibody |
|||
| CSB-PA082237- | Cusabio | 402 EUR | |
|
Description: A polyclonal antibody against AR (Ab-363). Recognizes AR (Ab-363) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
|||
AR (Ab-363) Antibody |
|||
| CSB-PA082237-100ul | Cusabio | 100ul | 379.2 EUR |
|
Description: A polyclonal antibody against AR (Ab-363). Recognizes AR (Ab-363) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
|||
Phospho-AR (Ser213) Antibody |
|||
| CSB-PA097994- | Cusabio | 402 EUR | |
|
Description: A polyclonal antibody against Phospho-AR (Ser213). Recognizes Phospho-AR (Ser213) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200 |
|||
Phospho-AR (Ser213) Antibody |
|||
| CSB-PA097994-100ul | Cusabio | 100ul | 434.4 EUR |
|
Description: A polyclonal antibody against Phospho-AR (Ser213). Recognizes Phospho-AR (Ser213) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200 |
|||
AR Antibody, HRP conjugated |
|||
| 1-CSB-PA05979B0Rb | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
|||
AR Antibody, FITC conjugated |
|||
| 1-CSB-PA05979C0Rb | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
|||
AR Antibody, Biotin conjugated |
|||
| 1-CSB-PA05979D0Rb | Cusabio |
|
|
|
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
|||
AR-Alpha1D Polyclonal Antibody |
|||
| ABP53865-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1D from Human. This AR-Alpha1D antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1D at AA rangle: 420-500 |
|||
AR-Alpha1D Polyclonal Antibody |
|||
| ABP53865-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1D from Human. This AR-Alpha1D antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1D at AA rangle: 420-500 |
|||
AR-Alpha1D Polyclonal Antibody |
|||
| ABP53865-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1D from Human. This AR-Alpha1D antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1D at AA rangle: 420-500 |
|||
AR-Alpha1B Polyclonal Antibody |
|||
| ABP53874-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1B from Human, Mouse, Rat. This AR-Alpha1B antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1B at AA rangle: 410-490 |
|||
AR-Alpha1B Polyclonal Antibody |
|||
| ABP53874-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1B from Human, Mouse, Rat. This AR-Alpha1B antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1B at AA rangle: 410-490 |
|||
AR-Alpha1B Polyclonal Antibody |
|||
| ABP53874-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1B from Human, Mouse, Rat. This AR-Alpha1B antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1B at AA rangle: 410-490 |
|||
AR-Alpha1A Polyclonal Antibody |
|||
| ABP53880-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1A from Human, Mouse, Rat. This AR-Alpha1A antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR-?1A at AA rangle: 110-190 |
|||
AR-Alpha1A Polyclonal Antibody |
|||
| ABP53880-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1A from Human, Mouse, Rat. This AR-Alpha1A antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR-?1A at AA rangle: 110-190 |
|||
AR-Alpha1A Polyclonal Antibody |
|||
| ABP53880-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1A from Human, Mouse, Rat. This AR-Alpha1A antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR-?1A at AA rangle: 110-190 |
|||
AR-Alpha1A Polyclonal Antibody |
|||
| ABP53881-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1A from Human. This AR-Alpha1A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1A at AA rangle: 310-390 |
|||
AR-Alpha1A Polyclonal Antibody |
|||
| ABP53881-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1A from Human. This AR-Alpha1A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1A at AA rangle: 310-390 |
|||
AR-Alpha1A Polyclonal Antibody |
|||
| ABP53881-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha1A from Human. This AR-Alpha1A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR-?1A at AA rangle: 310-390 |
|||
AR Alpha2A Polyclonal Antibody |
|||
| ABP53894-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR Alpha2A from Human, Mouse, Rat. This AR Alpha2A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR ?2A at AA rangle: 300-380 |
|||
AR Alpha2A Polyclonal Antibody |
|||
| ABP53894-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR Alpha2A from Human, Mouse, Rat. This AR Alpha2A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR ?2A at AA rangle: 300-380 |
|||
AR Alpha2A Polyclonal Antibody |
|||
| ABP53894-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR Alpha2A from Human, Mouse, Rat. This AR Alpha2A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human AR ?2A at AA rangle: 300-380 |
|||
AR-Alpha2A Polyclonal Antibody |
|||
| ABP53895-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha2A from Human. This AR-Alpha2A antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR-?2A at AA rangle: 250-330 |
|||
AR-Alpha2A Polyclonal Antibody |
|||
| ABP53895-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha2A from Human. This AR-Alpha2A antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR-?2A at AA rangle: 250-330 |
|||
AR-Alpha2A Polyclonal Antibody |
|||
| ABP53895-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of AR-Alpha2A from Human. This AR-Alpha2A antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR-?2A at AA rangle: 250-330 |
|||
AR Alpha2B Polyclonal Antibody |
|||
| ABP53900-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of AR Alpha2B from Human. This AR Alpha2B antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR ?2B at AA rangle: 130-210 |
|||
.A believable mannequin for this underlying distribution of phrase counts is given by means of modeling the DNA sequence as a Markov chain (MC). For single lengthy sequences, environment friendly statistics can be found to estimate the order of MCs and the transition chance matrix for the sequences. As NGS knowledge don’t present a single lengthy sequence, inference strategies on Markovian properties of sequences based mostly on single lengthy sequences can’t be instantly used for NGS quick learn knowledge.
cdna avm
gelson’s rancho mirage
gelson’s thousand oaks
gelson’s weekly flyer
gelsosomo’s crown point
gelsosomo’s pizza
gelsosomo’s pizza chesterton
gelston house east haddam ct
gelstx
gelsyn injection
gelsyn-3
gelsyn-3 injection
isotopes and ions
isotopes baseball
isotopes baseball abq
isotopes definition
isotopes examples
isotopes of argon
isotopes of copper
isotopes of hydrogen
isotopes of lead
isotopes of nitrogen
nattrol strep a
nattrol vaginal panel zeptometrix
panel app
panel beater
panel beds
panel champ
panel control
panel de control
reagents definition
reagents eso
reagents for corona testing
reagents for organic synthesis
reagents nc
reagents needed for test
reagents qc
reagents s.a
reagents sds
reagents that break double bonds
reagents undercity
reagents used for pcr
reagents usp
reagents vendor
reagents vendor orgrimmar
reagents vendor tb