We current proof that the sign recognition particle (SRP) acknowledges sign sequences through the NG area on the SRP54 protein subunit. Utilizing a just lately developed cross-linking methodology (Fancy, D. A., and Kodadek, T. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6020-6024; Correction (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1317), we discover that sign peptides cross-link to the Escherichia coli SRP protein Ffh (the homologue of the mammalian SRP54 subunit) through the NG area.
Inside the NG area, the cross-linking web site maps to the ras-like C-terminal subdomain termed the G area. This consequence stands in distinction to earlier research, which concluded based mostly on nascent chain cross-linking that the sign sequence certain to the adjoining M area. As unbiased proof of a direct binding interplay between the NG area and the sign sequence, we discover that the NG area of Ffh binds sign peptides as an remoted entity. Our outcomes recommend that the NG area types a considerable a part of the binding web site for the sign sequence.

p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Built-in Pulsed Secure Isotope Labeling With Amino Acids in Cell Tradition (pSILAC) and Subsequent Era Sequencing (NGS) Analyses.

We decided the impact of p53 activation on de novo protein synthesis utilizing quantitative proteomics (pulsed secure isotope labeling with amino acids in cell tradition/pSILAC) within the colorectal most cancers cell line SW480. This was mixed with mRNA and noncoding RNA expression analyses by subsequent technology sequencing (RNA-, miR-Seq). Moreover, genome-wide DNA binding of p53 was analyzed by chromatin-immunoprecipitation (ChIP-Seq).
Thereby, we recognized differentially regulated proteins (542 up, 569 down), mRNAs (1258 up, 415 down), miRNAs (111 up, 95 down) and lncRNAs (270 up, 123 down). Modifications in protein and mRNA expression ranges confirmed a constructive correlation (r = 0.50, p < 0.0001). In whole, we detected 133 direct p53 goal genes that had been differentially expressed and displayed p53 occupancy within the neighborhood of their promoter.
Extra transcriptionally induced genes displayed occupied p53 binding websites (4.3% mRNAs, 7.2% miRNAs, 6.3% lncRNAs, 5.9% proteins) than repressed genes (2.4% mRNAs, 3.2% miRNAs, 0.8% lncRNAs, 1.9% proteins), suggesting oblique mechanisms of repression. Round 50% of the down-regulated proteins displayed seed-matching sequences of p53-induced miRNAs within the corresponding 3′-UTRs.
Furthermore, proteins repressed by p53 considerably overlapped with these beforehand proven to be repressed by miR-34a. We confirmed up-regulation of the novel direct p53 goal genes LINC01021, MDFI, ST14 and miR-486 and confirmed that ectopic LINC01021 expression inhibits proliferation in SW480 cells. Moreover, KLF12, HMGB1 and CIT mRNAs had been confirmed as direct targets of the p53-induced miR-34a, miR-205 and miR-486-5p, respectively.
Mapping the signal sequence-binding site on SRP reveals a significant role for the NG domain.
According to the lack of p53 operate throughout tumor development, elevated expression of KLF12, HMGB1 and CIT was detected in superior phases of most cancers. In conclusion, the combination of a number of omics strategies allowed the excellent identification of direct and oblique effectors of p53 that present new insights and leads into the mechanisms of p53-mediated tumor suppression.

Subsequent-generation sequencing (NGS) for evaluation of microbial water high quality: present progress, challenges, and future alternatives.

Water high quality is an emergent property of a posh system comprised of interacting microbial populations and launched microbial and chemical contaminants. Research leveraging next-generation sequencing (NGS) applied sciences are offering new insights into the ecology of microbially mediated processes that affect contemporary water high quality reminiscent of algal blooms, contaminant biodegradation, and pathogen dissemination. As well as, sequencing strategies focusing on small subunit (SSU) rRNA hypervariable areas have allowed identification of signature microbial species that function bioindicators for sewage contamination in these environments.
Past amplicon sequencing, metagenomic and metatranscriptomic analyses of microbial communities in contemporary water environments reveal the genetic capabilities and interaction of waterborne microorganisms, shedding gentle on the mechanisms for manufacturing and biodegradation of poisons and different contaminants. This evaluate discusses the challenges and advantages of making use of NGS-based strategies to water high quality analysis and evaluation.
We’ll contemplate the suitability and biases inherent within the software of NGS as a screening software for evaluation of organic dangers and talk about the potential and limitations for direct quantitative interpretation of NGS knowledge.
Secondly, we’ll study case research from latest literature the place NGS based mostly strategies have been utilized to matters in water high quality evaluation, together with growth of bioindicators for sewage air pollution and microbial supply monitoring, characterizing the distribution of toxin and antibiotic resistance genes in water samples, and investigating mechanisms of biodegradation of dangerous pollution that threaten water high quality. Lastly, we offer a brief evaluate of rising NGS platforms and their potential purposes to the subsequent technology of water high quality evaluation instruments.

Inference of Markovian properties of molecular sequences from NGS knowledge and purposes to comparative genomics.

Subsequent-generation sequencing (NGS) applied sciences generate massive quantities of quick learn knowledge for a lot of totally different organisms. The truth that NGS reads are typically quick makes it difficult to assemble the reads and reconstruct the unique genome sequence. For clustering genomes utilizing such NGS knowledge, word-count based mostly alignment-free sequence comparability is a promising method, however for this method, the underlying anticipated phrase counts are important

Beckman Tungsten Lamp
LT-BEC-100 Scientific Laboratory Supplies EACH 58.8 EUR

Jasco V500. 50 Tungsten Lamp
LT-JAS-102 Scientific Laboratory Supplies EACH 58.8 EUR

ICP Std Tungsten 1000ug/mL in 2% NH4OH
PW2A7 Scientific Laboratory Supplies 100ML 221.95 EUR

ICP Std Tungsten 1000ug/mL in 2% NH4OH
PW2B7 Scientific Laboratory Supplies 250ML 359.04 EUR

ICP Std Tungsten 1000ug/mL in 2% NH4OH
PW2C7 Scientific Laboratory Supplies 500ML 489.6 EUR

ICP Std Tungsten 10000ug/mL in 2% NH4OH
PW4A7 Scientific Laboratory Supplies 100ML 386.46 EUR

ICP Std Tungsten 10000ug/mL in 2% NH4OH
PW4B7 Scientific Laboratory Supplies 250ML 462.18 EUR

Kinesis TSP uV100/1000/2000/3000 Tungsten Lamp
CHR6115 Scientific Laboratory Supplies EACH 716.4 EUR

Dionex Ultimate 3000 Tungsten Lamp
LT-DIO-105 Scientific Laboratory Supplies EACH 387.6 EUR

SKINNER LIST ACID EXTRACTABLES 1mL
SKINNER-AE Scientific Laboratory Supplies 1ML 183.6 EUR

Unicam 5625 5675 8600 8700 8800 Series Tungsten Lamp
LT-PHU-102 Scientific Laboratory Supplies EACH 177.6 EUR

Lamp Shimadzu Spec. Tungsten
IZ06265005AT Scientific Laboratory Supplies EACH 49.74 EUR

Kinesis TSP uV6000 Tungsten Lamp
CHR6116 Scientific Laboratory Supplies EACH 385.2 EUR

Shimadzu M10AVP Tungsten Lamp
LT-SHI-104 Scientific Laboratory Supplies EACH 57.6 EUR

Sodium tungstate dihydrate
GK6152-100G Glentham Life Sciences 100 g 79.2 EUR

Sodium tungstate dihydrate
GK6152-250G Glentham Life Sciences 250 g 122.4 EUR

Sodium tungstate dihydrate
GK6152-25G Glentham Life Sciences 25 g 56.4 EUR

Sodium tungstate dihydrate
GK6152-500G Glentham Life Sciences 500 g 189.6 EUR

Sodium tungstate, dihydrate
S0898 Bio Basic 250g 130.99 EUR

Cecil Series 2. 1000 to 9000. CE Sereis Tungsten Lamp
LT-CEC-111 Scientific Laboratory Supplies EACH 106.8 EUR

Viral Nucleic Acid Extraction KitDNA/RNA
FYG401-100P Yeastern Biotech 100 Preps Ask for price

Viral Nucleic Acid Extraction KitDNA/RNA
FYG401-300P Yeastern Biotech 300 Preps Ask for price

Viral Nucleic Acid Extraction KitDNA/RNA
FYG401-50P Yeastern Biotech 50 Preps Ask for price

Assurance Grade Tungsten for AA and ICP 1000 ug/mL (1000 PPM) 30mL in H2O
PLW9-2M Scientific Laboratory Supplies 30ML 34.8 EUR

Assurance Grade Tungsten for AA and ICP 1000 ug/mL (1000 PPM) 500mL in H2O
PLW9-2X Scientific Laboratory Supplies 500ML 150 EUR

Assurance Grade Tungsten for AA and ICP 1000 ug/mL (1000 PPM) 125mL in H2O
PLW9-2Y011 Scientific Laboratory Supplies 125ML 66 EUR

Assurance Grade Tungsten for AA and ICP 10000 ug/mL (10000 PPM) 500mL in H2O
PLW9-3X Scientific Laboratory Supplies 500ML 273.6 EUR

Assurance Grade Tungsten for AA and ICP 10000 ug/mL (10000 PPM) 125mL in H2O
PLW9-3Y Scientific Laboratory Supplies 125ML 116.4 EUR

Shimadzu SPD-10AV. AVP. AVVP. 20AV Tungsten Lamp
LT-SHI-101 Scientific Laboratory Supplies EACH 273.6 EUR

Assurance Grade Tungsten for AA and ICP 1000 ug/mL (1000 PPM) 500mL in 1% HNO3 / 2% HF
PLW2-2X Scientific Laboratory Supplies 500ML 158.4 EUR

Assurance Grade Tungsten for AA and ICP 10000 ug/mL (10000 PPM) 500mL in 2% HNO3 / 5% HF
PLW2-3X Scientific Laboratory Supplies 500ML 272.4 EUR

Viral Nucleic Acid Extraction Kit II (50prep)
FAVNK-002 Favorgen 50 preps 198 EUR

Viral Nucleic Acid Extraction Kit II (100prep)
FAVNK-002-1 Favorgen 100 preps 259.2 EUR

Viral Nucleic Acid Extraction Kit II (300prep)
FAVNK-002-2 Favorgen 300 preps 476.4 EUR

Kinesis Hollow Cathode Lamp Tungsten 37mm Std
CHR6070 Scientific Laboratory Supplies EACH 334.23 EUR

Claritas PPT Grade Tungsten for ICP-MS 1 ug/mL (1 PPM) 125mL in 2% HNO3 / tr HF
CLW2-1BY Scientific Laboratory Supplies 125ML 117.6 EUR

vamPure™ Blood Nucleic Acid Extraction Kit
K5011720 Biochain 1 kit 245 EUR

Kinesis Hollow Cathode Lamp Tungsten 37mm unicam
CHR6071 Scientific Laboratory Supplies EACH 385.15 EUR

Kinesis Hollow Cathode Lamp Tungsten 37mm Varian
CHR6072 Scientific Laboratory Supplies EACH 385.15 EUR

Two (2) GAGG Sentinel Beamstop with Tungsten Housing
DBS-GAGGBS-2-B MiTeGen 2 UNITS 5358 EUR
Description: Two (2) GAGG Sentinel Beamstop with Tungsten Housing

TCLP Base/Neutral/Acid Extractable Spike Solution
TCLP-BNA Scientific Laboratory Supplies 1ML 80.4 EUR

TCLP Base/Neutral/Acid Extractable Spike Solution
TCLP-BNA-5 Scientific Laboratory Supplies 5ML 386.4 EUR

LKB Pharmacia Ultrospec 2000 3000 Novaspec ii Tungsten Lamp
LT-LKB-100 Scientific Laboratory Supplies EACH 49.2 EUR

Unicam UV1 Helios Alpha. Beta Gamma and Delta Tungsten Lamp
LT-PHU-103 Scientific Laboratory Supplies EACH 136.8 EUR

Kinesis Hollow Cathode Lamp Tungsten 50mm Standard
CHR6073 Scientific Laboratory Supplies EACH 488.29 EUR

Acid Extractables Surrogate Mix (3) (2000ppm) - 5.5mL Bottle
ECS-N-003 Scientific Laboratory Supplies 5.5ML 61.2 EUR

Acid Extractables Surrogate Mix (4) (2000ppm) - 5.5mL Bottle
ECS-N-023 Scientific Laboratory Supplies 5.5ML 115.2 EUR

Acid Extractables Surrogate Mix (3) (2000ppm) - 11.5mL Bottle
ECS-Z-003 Scientific Laboratory Supplies 11.5ML 114 EUR

JBS Tungstate Cluster Kit; contains 3 different clusters
M-PK-108 MiTeGen 10.5 mg 178 EUR
Description: JBS Tungstate Cluster Kit; contains 3 different clusters

Kinesis Hollow Cathode Lamp Tungsten 50mm PE AAnalyst (Lumina)
CHR6074 Scientific Laboratory Supplies EACH 617.55 EUR

Acid Extractables Surrogate Mix 4 component-10.5mL Bottle
ECS-Z-023 Scientific Laboratory Supplies 10.5ML 213.6 EUR

IKA M 22 hard tungsten carbide cutter for materials upto Mohs hardness 8
MIL2132 Scientific Laboratory Supplies EACH 534 EUR

xTractPure™ Cell and Tissue Nucleic Acid Extraction Kit
Z2212005 Biochain 1 kit (96 extractions) 449 EUR

AnaPrep Viral Nucleic Acid Extraction Kit (48) For extracting viral nucleic acids from plasma
Z1322003 Biochain 1 kit (48 extractions) Including all required plastic disposables 216 EUR

EpiQuik Nuclear Extraction Kit II (Nucleic Acid-Free) 
OP-0022 EpiGentek
  • 350.58 EUR
  • 206.80 EUR
  • 100 Extractions
  • 100 Extractions

Xpert Nuclear Protein Extraction Kit, Nucleic acid free
N2200-050 GenDepot 50 ext Ask for price

Xpert Nuclear Protein Extraction Kit, Nucleic acid free
N2200-100 GenDepot 100 ext Ask for price

AnaPrep Viral Nucleic Acid Large Volume Extraction Kit
Z1322016 Biochain 1 kit (48 extractions) Including all required plastic disposables 419 EUR

Viral Nucleic Acid Extraction Kit (Proteinase K & Carrier RNA included)
RD05 GeneOn 5 preps Ask for price

Viral Nucleic Acid Extraction Kit (Proteinase K & Carrier RNA included)
RD25 GeneOn 25 preps 120 EUR

Viral Nucleic Acid Extraction Kit (Proteinase K & Carrier RNA included)
RD50 GeneOn 50 preps 165.6 EUR

GAGG Sentinel Beam Stops - Generation 2 with Tungsten Housing and GAGG Scintillator - Qty 1
DBS-GAGGBS-1-B MiTeGen 1 UNIT 2785 EUR
Description: GAGG Sentinel Beam Stops - Generation 2 with Tungsten Housing and GAGG Scintillator - Qty 1

Polyclonal Excitatory Amino Acid Transporter 1 (extracellular) Antibody
APR11871G Leading Biology 0.05ml 790.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Excitatory Amino Acid Transporter 1 (extracellular) . This antibody is tested and proven to work in the following applications:

Viral Nucleic Acid Extraction Kit I (50prep), (With Carrier RNA, for low viral load specimen using carrier RNA)
FAVNK-001 Favorgen 50 preps 198 EUR

Viral Nucleic Acid Extraction Kit I (100prep), (With Carrier RNA, for low viral load specimen using carrier RNA)
FAVNK-001-1 Favorgen 100 preps 259.2 EUR

Viral Nucleic Acid Extraction Kit I (300prep), (With Carrier RNA, for low viral load specimen using carrier RNA)
FAVNK-001-2 Favorgen 300 preps 476.4 EUR

Okadaic acid, free acid
OL1198 Bio Basic 50ug 231.22 EUR

Fumalic acid(Ferulic acid)
E1KS2300 EnoGene 50mg 390 EUR

Octanoic acid (Caorylic acid)
O5678 Bio Basic 250ml 80.88 EUR

DL-Maleic acid (Toxilic acid)
MA0333 Bio Basic 250g 77.4 EUR

D-Glucuronic acid, free acid
GB0482 Bio Basic 5g 186.19 EUR

Ar/ Rat Ar ELISA Kit
ELI-04146r Lifescience Market 96 Tests 1063.2 EUR

MUCOBROMIC ACID (2,3‐ DIBROMOMALEALDEHYDIC ACID)
613004 Survival Technologies each Ask for price

AnaPrep Viral/Pathogen Nucleic Acids Extraction Kit A
Z1322011 Biochain 1 kit (48 extractions) Including all required plastic disposables 216 EUR

AnaPrep Viral/Pathogen Nucleic Acids Extraction Kit B
Z1322012 Biochain 1 kit (48 extractions) Including all required plastic disposables 246 EUR

Tide Quencher™ 1 acid [TQ1 acid]
2190 AAT Bioquest 100 mg 222 EUR

Tide Quencher™ 2 acid [TQ2 acid]
2200 AAT Bioquest 100 mg 222 EUR

Tide Quencher™ 3 acid [TQ3 acid]
2220 AAT Bioquest 100 mg 222 EUR

Rat Uric Acid(Uric Acid) ELISA Kit
YLA1447RA-48T Shanghai YL Biotech 48T 465 EUR

Rat Uric Acid(Uric Acid) ELISA Kit
YLA1447RA-96T Shanghai YL Biotech 96T 600 EUR

Human Uric Acid(Uric Acid) ELISA Kit
QY-E05411 Qayee Biotechnology 96T 433.2 EUR

Human Uric Acid(Uric Acid) ELISA Kit
YLA3946HU-48T Shanghai YL Biotech 48T 435 EUR

Human Uric Acid(Uric Acid) ELISA Kit
YLA3946HU-96T Shanghai YL Biotech 96T 562.5 EUR

ICG acid
189 AAT Bioquest 5 mg 222 EUR

Tide Quencher™ 3WS acid [TQ3WS acid]
2227 AAT Bioquest 5 mg 222 EUR

Tide Quencher™ 2WS acid [TQ2WS acid]
2050 AAT Bioquest 25 mg 222 EUR

Tide Quencher™ 4WS acid [TQ4WS acid]
2060 AAT Bioquest 5 mg 222 EUR

Tide Quencher™ 5WS acid [TQ5WS acid]
2075 AAT Bioquest 5 mg 222 EUR

Tide Quencher™ 6WS acid [TQ6WS acid]
2090 AAT Bioquest 5 mg 334 EUR

Tide Quencher™ 7WS acid [TQ7WS acid]
2105 AAT Bioquest 5 mg 558 EUR

Bovine Uric Acid (Uric Acid) ELISA Kit
YLA0364BO-48T Shanghai YL Biotech 48T 502.5 EUR

Bovine Uric Acid (Uric Acid) ELISA Kit
YLA0364BO-96T Shanghai YL Biotech 96T 618.75 EUR

Canine Uric Acid(Uric Acid) ELISA Kit
YLA0205CA-48T Shanghai YL Biotech 48T 502.5 EUR

Canine Uric Acid(Uric Acid) ELISA Kit
YLA0205CA-96T Shanghai YL Biotech 96T 618.75 EUR

Human D-lactic acid(D-lactic acid)
QY-E05453 Qayee Biotechnology 96T 433.2 EUR

Rat Lactic acid(lactic acid)ELISA Kit
YLA1391RA-48T Shanghai YL Biotech 48T 465 EUR

Rat Lactic acid(lactic acid)ELISA Kit
YLA1391RA-96T Shanghai YL Biotech 96T 600 EUR

Uric acid
HY-B2130 MedChemExpress 500mg 129.6 EUR

Uric acid
UB0978 Bio Basic 10g 79.84 EUR

AR antibody
10R-2031 Fitzgerald 100 ul 483.6 EUR
Description: Mouse monoclonal AR antibody

AR antibody
70R-35838 Fitzgerald 100 ug 392.4 EUR
Description: Rabbit polyclonal AR antibody

AR-A014418
A3184-10 ApexBio 10 mg 153.6 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-A014418
A3184-5.1 ApexBio 10 mM (in 1mL DMSO) 147.6 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-A014418
A3184-50 ApexBio 50 mg 321.6 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-A014418
A3184-S ApexBio Evaluation Sample 97.2 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-C155858
A3185-10 ApexBio 10 mg 1189.2 EUR
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members.

AR-C155858
A3185-5 ApexBio 5 mg 733.2 EUR
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members.

AR-C155858
A3185-50 ApexBio 50 mg 3360 EUR
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members.

AR Antibody
ABD6783 Lifescience Market 100 ug 525.6 EUR

AR Antibody
32572-100ul SAB 100ul 302.4 EUR

AR A014418
20-abx076761 Abbexa
  • 861.60 EUR
  • 376.80 EUR
  • 25 mg
  • 5 mg

AR Antibody
AF6137 Affbiotech 200ul 420 EUR

AR Antibody
AF6927 Affbiotech 100ul 420 EUR

AR-C155858
B2743-1 Biovision 1 mg 417.6 EUR

AR 231453
B3269-10 ApexBio 10 mg 294 EUR
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors.

AR 231453
B3269-5 ApexBio 5 mg 214.8 EUR
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors.

AR 231453
B3269-5.1 ApexBio 10 mM (in 1mL DMSO) 234 EUR
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors.

AR Antibody
BF0349 Affbiotech 200ul 540 EUR

AR Antibody
BF0418 Affbiotech 200ul 540 EUR

AR Antibody
CSB-PA001975KA01HU- Cusabio each 402 EUR
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, ICC;WB:1:500-1:1000, IHC:1:50-1:100, ICC:1:50-1:100

AR Antibody
CSB-PA001975KA01HU-100ul Cusabio 100ul 466.8 EUR
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, ICC;WB:1:500-1:1000, IHC:1:50-1:100, ICC:1:50-1:100

AR siRNA
20-abx900461 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

AR siRNA
20-abx908237 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

AR siRNA
20-abx908238 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

AR Antibody
DF6783 Affbiotech 200ul 420 EUR

AR Antibody
1-CSB-PA011255 Cusabio
  • 266.40 EUR
  • 234.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

AR Antibody
1-CSB-PA011256 Cusabio
  • 266.40 EUR
  • 234.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/40000

AR Antibody
1-CSB-PA011257 Cusabio
  • 266.40 EUR
  • 234.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000

AR Antibody
1-CSB-PA011258 Cusabio
  • 266.40 EUR
  • 234.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

AR Antibody
1-CSB-PA006094 Cusabio
  • 266.40 EUR
  • 234.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

AR Antibody
1-CSB-PA056943 Cusabio
  • 380.40 EUR
  • 292.80 EUR
  • 100ul
  • 50ul
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100

AR Antibody
1-CSB-PA05979A0Rb Cusabio
  • 380.40 EUR
  • 402.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

AR-A014418
HY-10512 MedChemExpress 50mg 410.4 EUR

AR-9281
HY-111151 MedChemExpress 5mg 253.2 EUR

AR-C155858
HY-13248 MedChemExpress 10mM/1mL 579.6 EUR

AR-08
HY-U00371 MedChemExpress 20mg 16126.8 EUR

AR 231453
HY-15564 MedChemExpress 10mM/1mL 192 EUR

AR Antibody
F42684-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].

AR Antibody
F42850-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: The androgen receptor, also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding either of the androgenic hormones, testosterone, or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. It is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the AR is as a DNA-binding transcription factor that regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. [Wiki]

pCDNA3.1-AR
PVT18102 Lifescience Market 2 ug 360 EUR

Clematichinenoside AR
TBW00371 ChemNorm 10mg 1016.4 EUR

ar-Tumerone
TBW01373 ChemNorm 5mg Ask for price

Folic Acid
AT062 Unibiotest 1mg 1134 EUR

Folic acid
abx082263-100g Abbexa 100 g 376.8 EUR

Folic acid
20-abx082265 Abbexa
  • 376.80 EUR
  • 276.00 EUR
  • 100 g
  • 25 g

Boric acid
abx082355-500g Abbexa 500 g 243.6 EUR
.A believable mannequin for this underlying distribution of phrase counts is given by means of modeling the DNA sequence as a Markov chain (MC). For single lengthy sequences, environment friendly statistics can be found to estimate the order of MCs and the transition chance matrix for the sequences. As NGS knowledge don’t present a single lengthy sequence, inference strategies on Markovian properties of sequences based mostly on single lengthy sequences can’t be instantly used for NGS quick learn knowledge.