The cucumber (Cucumis sativus L.) reveals intensive variations in fruit measurement and form. Fruit size is a crucial agronomic and domesticated trait managed by quantitative trait loci (QTLs). Nonetheless, the underlying molecular and genetic mechanisms that decide cucumber fruit size stay unclear. QTL-seq is an environment friendly technique for QTL identification that takes benefit of bulked-segregant evaluation (BSA) and next-generation sequencing (NGS).
Within the current examine, we performed QTL mapping and QTL-seq of cucumber fruit size. QTL mapping recognized eight QTLs for immature and mature fruit size. A significant-effect QTL fl3.2, which defined a most of 38.87% of the phenotypic variation, was detected. A genome-wide comparability of SNP profiles between two DNA bulks recognized 6 QTLs for ovary size. QTLs ovl3.1 and ovl3.2 each had main results on ovary size with a △ (SNP-index) of 0.80 (P < 0.01) and 0.74 (P < 0.01), respectively.
Quantitative RT-PCR of fruit size-related homologous genes localized within the consensus QTL FL3.2 was performed. 4 candidate genes exhibited elevated expression ranges in lengthy fruit genotypes. Our outcomes demonstrated the ability of the QTL-seq methodology in speedy QTL detection and supplied dependable QTL areas for fantastic mapping of fruit length-related loci and for figuring out candidate genes.

Dependable multiplex sequencing with uncommon index mis-assignment on DNB-based NGS platform.

Massively-parallel-sequencing, coupled with pattern multiplexing, has made genetic exams broadly inexpensive. Nonetheless, intractable index mis-assignments (generally exceeds 1%) have been repeatedly reported on some extensively used sequencing platforms.Right here, we investigated this high quality subject on BGI sequencers utilizing three library preparation strategies: complete genome sequencing (WGS) with PCR, PCR-free WGS, and two-step focused PCR.
Rapid identification of fruit length loci in cucumber (Cucumis sativus L.) using next-generation sequencing (NGS)-based QTL analysis.
BGI’s sequencers make the most of a novel DNA nanoball (DNB) expertise which makes use of rolling circle replication for DNA-nanoball preparation; this linear amplification is PCR free and might keep away from error accumulation. We demonstrated that single index mis-assignment from free listed oligos happens at a fee of 1 in 36 million reads, suggesting just about no index hopping throughout DNB creation and arraying.
Moreover, the DNB-based NGS libraries have achieved an unprecedentedly low sample-to-sample mis-assignment fee of 0.0001 to 0.0004% underneath really helpful procedures.Single indexing with DNB expertise supplies a easy however efficient methodology for delicate genetic assays with giant pattern numbers.

Subsequent-generation sequencing of immunoglobulin gene rearrangements for clonality evaluation: a technical feasibility examine by EuroClonality-NGS.

One of many hallmarks of B lymphoid malignancies is a B cell clone characterised by a novel footprint of clonal immunoglobulin (IG) gene rearrangements that serves as a diagnostic marker for clonality evaluation. The EuroClonality/BIOMED-2 assay is presently the gold customary for analyzing IG heavy chain (IGH) and κ mild chain (IGK) gene rearrangements of suspected B cell lymphomas.
Right here, the EuroClonality-NGS Working Group presents a multicentre technical feasibility examine of a novel method involving next-generation sequencing (NGS) of IGH and IGK loci rearrangements that’s extremely appropriate for detecting IG gene rearrangements in frozen and formalin-fixed paraffin-embedded tissue specimens.
By using gene-specific primers for IGH and IGK amplifying smaller amplicon sizes together with deep sequencing expertise, this NGS-based IG clonality evaluation confirmed strong efficiency, even in DNA samples of suboptimal DNA integrity, and a excessive medical sensitivity for the detection of clonal rearrangements.
Bioinformatics analyses of the high-throughput sequencing knowledge with ARResT/Interrogate, a platform developed inside the EuroClonality-NGS Working Group, allowed correct identification of clonotypes in each polyclonal cell populations and monoclonal lymphoproliferative problems. This multicentre feasibility examine is a crucial step in direction of implementation of NGS-based clonality evaluation in medical observe, which is able to finally enhance lymphoma diagnostics.

Excessive-throughput evaluation of the actions of xCas9, SpCas9-NG and SpCas9 at matched and mismatched goal sequences in human cells.

The functions of clustered commonly interspaced quick palindromic repeats (CRISPR)-based genome modifying may be restricted by a scarcity of appropriate protospacer adjoining motifs (PAMs), inadequate on-target exercise and off-target results. Right here, we report an in depth comparability of the PAM-sequence compatibilities and the on-target and off-target actions of Cas9 from Streptococcus pyogenes (SpCas9) and the SpCas9 variants xCas9 and SpCas9-NG (that are identified to have broader PAM compatibility than SpCas9) at 26,478 lentivirally built-in goal sequences and 78 endogenous goal websites in human cells.
We discovered that xCas9 has the bottom tolerance for mismatched goal sequences and that SpCas9-NG has the broadest PAM compatibility. We additionally present, on the premise of newly recognized non-NGG PAM sequences, that SpCas9-NG and SpCas9 can edit six beforehand unedited endogenous websites related to genetic illnesses.

Mouse Androgen Receptor (AR) ELISA Kit
RD-AR-Mu-48Tests Reddot Biotech 48 Tests 511 EUR

Mouse Androgen Receptor (AR) ELISA Kit
RD-AR-Mu-96Tests Reddot Biotech 96 Tests 709 EUR

Rat Androgen Receptor (AR) ELISA Kit
RD-AR-Ra-48Tests Reddot Biotech 48 Tests 534 EUR

Rat Androgen Receptor (AR) ELISA Kit
RD-AR-Ra-96Tests Reddot Biotech 96 Tests 742 EUR

Human Androgen Receptor (AR) ELISA Kit
RDR-AR-Hu-48Tests Reddot Biotech 48 Tests 522 EUR

Human Androgen Receptor (AR) ELISA Kit
RDR-AR-Hu-96Tests Reddot Biotech 96 Tests 724 EUR

Mouse Androgen Receptor (AR) ELISA Kit
RDR-AR-Mu-48Tests Reddot Biotech 48 Tests 534 EUR

Mouse Androgen Receptor (AR) ELISA Kit
RDR-AR-Mu-96Tests Reddot Biotech 96 Tests 742 EUR

Rat Androgen Receptor (AR) ELISA Kit
RDR-AR-Ra-48Tests Reddot Biotech 48 Tests 558 EUR

Rat Androgen Receptor (AR) ELISA Kit
RDR-AR-Ra-96Tests Reddot Biotech 96 Tests 776 EUR

Ar/ Rat Ar ELISA Kit
ELI-04146r Lifescience Market 96 Tests 886 EUR

AR-08
HY-U00371 MedChemExpress 20mg 13439 EUR

AR-A014418
HY-10512 MedChemExpress 50mg 342 EUR

AR-9281
HY-111151 MedChemExpress 5mg 211 EUR

AR-C155858
HY-13248 MedChemExpress 10mM/1mL 483 EUR

AR 231453
HY-15564 MedChemExpress 10mM/1mL 160 EUR

AR A014418
20-abx076761 Abbexa
  • 718.00 EUR
  • 314.00 EUR
  • 25 mg
  • 5 mg

AR Antibody
32572-100ul SAB 100ul 252 EUR

AR-A014418
A3184-10 ApexBio 10 mg 128 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-A014418
A3184-5.1 ApexBio 10 mM (in 1mL DMSO) 123 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-A014418
A3184-50 ApexBio 50 mg 268 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-A014418
A3184-S ApexBio Evaluation Sample 81 EUR
Description: IC50: 104 ± 27 nMGlycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer?s disease (AD). AR-A014418 is a selective GSK-3 inhibitor.

AR-C155858
A3185-10 ApexBio 10 mg 991 EUR
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members.

AR-C155858
A3185-5 ApexBio 5 mg 611 EUR
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members.

AR-C155858
A3185-50 ApexBio 50 mg 2800 EUR
Description: AR-C155858 is a potent and selective inhibitor of monocarboxylate transporters MCT1 and MCT2 with Ki values of 2.3nM and less than 10 nM, respectively [1].MCT is a monocarboxylate transporter family with 14 members.

AR siRNA
20-abx900461 Abbexa
  • 551.00 EUR
  • 732.00 EUR
  • 15 nmol
  • 30 nmol

AR siRNA
20-abx908237 Abbexa
  • 551.00 EUR
  • 732.00 EUR
  • 15 nmol
  • 30 nmol

AR siRNA
20-abx908238 Abbexa
  • 551.00 EUR
  • 732.00 EUR
  • 15 nmol
  • 30 nmol

AR 231453
B3269-10 ApexBio 10 mg 245 EUR
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors.

AR 231453
B3269-5 ApexBio 5 mg 179 EUR
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors.

AR 231453
B3269-5.1 ApexBio 10 mM (in 1mL DMSO) 195 EUR
Description: AR 231453 is an agonist of GPR119 with EC50 value of 0.68nM [1].AR 231453 is the first subnanomolar agonist of GPR119. It is highly selective against GPR119 over a 76 receptor and enzyme profiling panel (CEREP) including the known incretin receptors.

AR Antibody
1-CSB-PA056943 Cusabio
  • 317.00 EUR
  • 244.00 EUR
  • 100ul
  • 50ul
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100

AR Antibody
1-CSB-PA05979A0Rb Cusabio
  • 317.00 EUR
  • 335.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

AR Antibody
1-CSB-PA011255 Cusabio
  • 222.00 EUR
  • 195.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

AR Antibody
1-CSB-PA011256 Cusabio
  • 222.00 EUR
  • 195.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/40000

AR Antibody
1-CSB-PA011257 Cusabio
  • 222.00 EUR
  • 195.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000

AR Antibody
1-CSB-PA011258 Cusabio
  • 222.00 EUR
  • 195.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

AR Antibody
CSB-PA001975KA01HU- Cusabio 335 EUR
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, ICC;WB:1:500-1:1000, IHC:1:50-1:100, ICC:1:50-1:100

AR Antibody
CSB-PA001975KA01HU-100ul Cusabio 100ul 389 EUR
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, ICC;WB:1:500-1:1000, IHC:1:50-1:100, ICC:1:50-1:100

AR Antibody
1-CSB-PA006094 Cusabio
  • 222.00 EUR
  • 195.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against AR. Recognizes AR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

AR Antibody
BF0418 Affbiotech 200ul 376 EUR
Description: AR antibody detects endogenous levels of total AR.

AR Antibody
DF6783 Affbiotech 200ul 304 EUR
Description: AR Antibody detects endogenous levels of total AR.

AR Antibody
ABD6783 Lifescience Market 100 ug 438 EUR

AR-C155858
B2743-1 Biovision 1 mg 348 EUR

Clematichinenoside AR
TBW00371 ChemNorm 10mg 847 EUR

ar-Tumerone
TBW01373 ChemNorm 5mg Ask for price

pCDNA3.1-AR
PVT18102 Lifescience Market 2 ug 300 EUR

AR antibody
10R-2031 Fitzgerald 100 ul 403 EUR
Description: Mouse monoclonal AR antibody

AR antibody
70R-35838 Fitzgerald 100 ug 327 EUR
Description: Rabbit polyclonal AR antibody

KAF/AR/ Rat KAF/ AR ELISA Kit
ELA-E0006r Lifescience Market 96 Tests 886 EUR

AR Polyclonal Antibody
ES5938-100ul ELK Biotech 100ul 279 EUR
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

AR Polyclonal Antibody
ES5938-50ul ELK Biotech 50ul 207 EUR
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

AR Polyclonal Antibody
ES5939-100ul ELK Biotech 100ul 279 EUR
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for IHC, WB, ELISA

AR Polyclonal Antibody
ES5939-50ul ELK Biotech 50ul 207 EUR
Description: A Rabbit Polyclonal antibody against AR from Human. This antibody is tested and validated for IHC, WB, ELISA

AR Polyclonal Antibody
ES5940-100ul ELK Biotech 100ul 279 EUR
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse. This antibody is tested and validated for IHC, IF, WB, ELISA

AR Polyclonal Antibody
ES5940-50ul ELK Biotech 50ul 207 EUR
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse. This antibody is tested and validated for IHC, IF, WB, ELISA

AR Polyclonal Antibody
ES5941-100ul ELK Biotech 100ul 279 EUR
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

AR Polyclonal Antibody
ES5941-50ul ELK Biotech 50ul 207 EUR
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

AR-42J cells
C0018004 Addexbio One Frozen vial 455 EUR

AR-C102222 (hydrochloride)
HY-12122A MedChemExpress 10mg 1175 EUR

AR Polyclonal Antibody
ES4268-100ul ELK Biotech 100ul 279 EUR
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

AR Polyclonal Antibody
ES4268-50ul ELK Biotech 50ul 207 EUR
Description: A Rabbit Polyclonal antibody against AR from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

AR Polyclonal Antibody
ABP54939-003ml Abbkine 0.03ml 158 EUR
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S650

AR Polyclonal Antibody
ABP54939-01ml Abbkine 0.1ml 289 EUR
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S650

AR Polyclonal Antibody
ABP54939-02ml Abbkine 0.2ml 414 EUR
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S650

AR Polyclonal Antibody
ABP54940-003ml Abbkine 0.03ml 158 EUR
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S213

AR Polyclonal Antibody
ABP54940-01ml Abbkine 0.1ml 289 EUR
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S213

AR Polyclonal Antibody
ABP54940-02ml Abbkine 0.2ml 414 EUR
Description: A polyclonal antibody for detection of AR from Human. This AR antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S213

AR Polyclonal Antibody
ABP54941-003ml Abbkine 0.03ml 158 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse. This AR antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S94

AR Polyclonal Antibody
ABP54941-01ml Abbkine 0.1ml 289 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse. This AR antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S94

AR Polyclonal Antibody
ABP54941-02ml Abbkine 0.2ml 414 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse. This AR antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of S94

AR Polyclonal Antibody
ABP54942-003ml Abbkine 0.03ml 158 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of Y363

AR Polyclonal Antibody
ABP54942-01ml Abbkine 0.1ml 289 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of Y363

AR Polyclonal Antibody
ABP54942-02ml Abbkine 0.2ml 414 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AR around the non-phosphorylation site of Y363

AR Polyclonal Antibody
ABP53269-003ml Abbkine 0.03ml 158 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR

AR Polyclonal Antibody
ABP53269-01ml Abbkine 0.1ml 289 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR

AR Polyclonal Antibody
ABP53269-02ml Abbkine 0.2ml 414 EUR
Description: A polyclonal antibody for detection of AR from Human, Mouse, Rat. This AR antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AR

AR (pS213) Antibody
20-abx000354 Abbexa
  • 495.00 EUR
  • 704.00 EUR
  • 356.00 EUR
  • 100 ul
  • 200 ul
  • 50 ul

AR (pS650) Antibody
20-abx000355 Abbexa
  • 495.00 EUR
  • 704.00 EUR
  • 356.00 EUR
  • 100 ul
  • 200 ul
  • 50 ul

Anti-AR antibody
STJ91659 St John's Laboratory 200 µl 197 EUR
Description: Rabbit polyclonal to AR.

Anti-AR antibody
STJ91660 St John's Laboratory 200 µl 197 EUR
Description: Rabbit polyclonal to AR.

Anti-AR antibody
STJ91661 St John's Laboratory 200 µl 197 EUR
Description: Rabbit polyclonal to AR.

Anti-AR antibody
STJ91662 St John's Laboratory 200 µl 197 EUR
Description: Rabbit polyclonal to AR.

Anti-AR antibody
STJ97233 St John's Laboratory 200 µl 197 EUR
Description: AR is a protein encoded by the AR gene which is approximately 99,1 kDa. AR is localised to the nucleus and cytoplasm. It is involved in deubiquitination, gene expression, metabolism of proteins and the nuclear receptor transcription pathway. It functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR is expressed in the liver, nervous system, blood, muscle and kidney. Mutations in the AR gene may result in prostate cancer. STJ97233 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR protein.

Anti-AR antibody
STJ97845 St John's Laboratory 100 µl 234 EUR
Description: Mouse monoclonal to AR.

Anti-AR antibody
STJ97846 St John's Laboratory 100 µl 234 EUR
Description: Mouse monoclonal to AR.

Anti-AR Antibody
STJ193178 St John's Laboratory 200 µl 197 EUR

Anti-AR antibody
STJ22662 St John's Laboratory 100 µl 277 EUR
Description: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.

AR ELISA Kit
STJ150094 St John's Laboratory 1 kit 412 EUR
Description: The kit is a competitive enzyme immunoassay for in vitro quantitative measurement of T in serum, plasma and other biological fluids

AR Polyclonal Antibody
40609-100ul SAB 100ul 252 EUR

AR Polyclonal Antibody
40609-50ul SAB 50ul 187 EUR

AR Polyclonal Antibody
40610-100ul SAB 100ul 252 EUR
Furthermore, we offer deep-learning fashions that predict the actions of xCas9 and SpCas9-NG on the goal sequences. The ensuing deeper understanding of the actions of xCas9, SpCas9-NG and SpCas9 in human cells ought to facilitate their use.